How to Build Purpose When Everything Has Been Lost

Vivienne Ming on finding true happiness through purpose beyond personal gain.

Highlights:

  • Dr. Ming believes purpose is something we build by contributing to something greater than ourselves, without seeking recognition or reward.
  • True, lasting happiness comes from eudaimonic experiences: meaningful actions like helping others or working toward a better future.
  • After facing homelessness and dropping out of college, Ming rebuilt her life through resilience, learning, and a drive to create social impact.
  • She applies technology, neuroscience, and storytelling to address real-world challenges such as Alzheimer’s, postpartum depression, and personalized diabetes care.
  • Ming uses storytelling to connect science with human beliefs, making complex issues emotionally relatable and easier to act upon.

All I’ve done is disappoint people. Why am I even here?

Vivienne Ming

“I didn’t know where my next meal would come from,” says Dr. Vivienne Ming, recalling the years she lived in a car parked off a California highway in the U.S. It was 1995, and she had hit rock bottom. Since childhood, expectations had been high. Her father, a physician, pushed her to achieve great things. Now, she had dropped out of college. Left her family. Everything. In crisis, she didn’t move. “All I’ve done is disappoint people. Why am I even here?” she asked herself over and over. What stopped her was the thought of what it would do to her parents. Then something shifted. In that moment of despair, something changed. “Maybe I’ll never be happy,” she thought. “But that doesn’t have to be the reason I’m alive.

I could live a life that improves the lives of others.

Vivienne Ming

“I spent most of the ‘90s, first dropping out of college, then becoming homeless,” recalls Vivienne, who often describes herself as a “professional mad scientist.” In 1999, she got the chance to return to university. “I completed the entire degree in one year and got perfect grades in every subject.” She narrowed her options to mathematics, economics, or cognitive neuroscience. She ruled out math and chose between the other two because she believed both could improve people’s lives. Then she flipped a coin. “It landed on heads, so I studied brains,” she says. In this process, she regained her confidence and with it, built an inner compass. “I could live a life that improves the lives of others.” Then, with a smile, she confesses, “Turns out I could be happy.

Vivienne distinguishes between two types of happiness. Hedonic happiness is fleeting and centered on immediate pleasure, like eating junk food, buying a shirt, or watching TV. “It’s not bad. You’re not a bad person for feeling it, don’t get me wrong. But it’s fleeting,” she clarifies. The other, eudaimonic happiness, comes from doing something meaningful, from having a purpose. Like those who plant a tree knowing they’ll never sit in its shade. Why do they do it? For someone else. For a future they won’t live to see. Something that doesn’t benefit them directly—but they do it anyway. “It all starts with purpose,” she affirms. Having it means acting without expecting personal gain. “Something bigger than yourself.”

You don’t find a purpose, you build it.

Vivienne Ming

“You don’t find a purpose, you build it,” she says. In fact, when she interviews someone, she uses a purpose-oriented thinking exercise. Before the interview, she asks them to think of a crazy project they’d be willing to do, even if no one ever knew it was their idea. No awards, just sacrifice. “What would you do?” That’s the only question she asks during job interviews for her lab, her companies, or her academic work. Then, during the interview, they work together to see if the idea can be improved collaboratively. If the outcome is better than what she could have come up with alone, the candidate gets the job.

That same logic of collaboration and shared purpose has translated into several initiatives. One of her postdocs, for example, founded OptoCeutics, a company focused on Alzheimer’s that aims to help people preserve their memory and identity for longer. Ming sits on its board. “Our joint research shows that it significantly slows Alzheimer’s progression,” she notes.

I’ve invented six completely different life-saving technologies over my career.

Vivienne Ming

This approach, applied across fields, has led Dr. Vivienne to develop multiple projects with direct impact on health and society. “I’ve invented six completely different life-saving technologies over my career.” One is Dionysus Digital Health, a company dedicated to maternal mental health that analyzes epigenetic biomarkers during pregnancy to predict the risk of postpartum depression. She also founded The Human Trust, an initiative aiming to transform healthcare, education, and opportunity systems, with a particular focus on privacy protection. In parallel, she created Socos Labs, a think tank dedicated to exploring the future of human potential.

My job, so to speak, is simply to make a difference.

Vivienne Ming

Her search for solutions extends into her personal life. When her son was diagnosed with diabetes at age seven, Vivienne designed an AI system that could interpret in real-time how his body responded to different foods. Connected to a glucose monitor and an insulin pump, the system learned to predict fluctuations in his blood sugar. “My job, so to speak, is simply to make a difference.”

Vivienne’s approach is driven by purpose. She doesn’t see herself as a traditional entrepreneur or consultant. She works “for the problem, philanthropically”, whether helping a family or a government tackle an issue. Likewise, she often starts these projects by funding them herself, with no expectation of return. Ultimately, she aims to create systemic change using science, data, and purpose to solve real problems affecting people who might otherwise be overlooked. “It’s almost never a tech problem. It’s almost always a misunderstanding of why people choose to do what they do,” she says.

Beliefs are driven by what people have lived. Their knowledge comes from what they know.

Vivienne Ming

For her, science is also tied to stories. Storytelling is a tool she uses to understand and communicate science. “Your job is to find the story that best connects all the research,” she explains. The goal isn’t perfection, but to get close to a truth that explains the world. Since dropping out of college, she found refuge in books, especially science fiction and fantasy.

During those dark times, reading gave her a way to imagine a different future. It gave her something to hold on to. A belief that the world could be better, and that maybe she could help make it so. “Beliefs are driven by what people have lived. Their knowledge comes from what they know.” These belief systems help explain why people make certain decisions. She’s realized that most people act more based on what they believe than on what they know. That’s why she uses stories that connect with people’s emotions and experiences to create real change—whether in public policy, business, or behavior. The story needs to be tailored to each audience because every audience believes in different things. “So when I tell a story, what I’m trying to do is connect the knowledge I’ve gained with the beliefs you already hold,” she says.

This ability to bridge scientific ideas with the human experience is also evident in her way of being. Vivienne constantly balances her intellect with humility. Despite her achievements, she reminds herself over and over that she is not someone special. “My work is important, but I am not,” she says. Although there’s a contradiction between what she has accomplished and how she sees herself, it doesn’t bother her. On the contrary, she’s embraced that contradiction as part of her identity. Instead of seeking external validation, she focuses on the impact of her work and on the belief that anyone, regardless of their background or past, can make a difference if they build a purpose and are willing to sacrifice for it. “That’s why purpose and meaning are so important,” she concludes.

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